Baby Vaccine Schedule: Every Shot, Every Age, and What to Expect

US baby vaccine schedule by age (CDC and AAP 2026), what to expect after shots, when to call the doctor, and how schedules differ by country.

Quick answer: In the US, the first-year schedule starts with hepatitis B at birth (and RSV protection in the first RSV season), then DTaP, polio (IPV), Hib, pneumococcal (PCV) and rotavirus at 2, 4 and 6 months, a yearly flu shot from 6 months, and MMR, chickenpox and hepatitis A from 12 months. Other countries use different schedules (see below). Most babies just get a sore leg, mild fussiness or a low fever for a day or two; if your baby is under 12 weeks and has a fever, call your pediatrician before giving any fever medicine.
Reviewed by: Whispie Editorial Team Evidence-Based Parenting Research

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This article is for general information and is not a substitute for professional medical advice. Always consult your pediatrician or doctor about your child.

Sources: WHO, CDC, AAP and NHS guidance. Recommendations differ between countries — for local advice see the NHS or CDC.

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Why Vaccines Matter

Before measles vaccination became widespread, the disease caused an estimated 2.6 million deaths a year worldwide (WHO). Babies get some antibodies from their mother, but that protection lasts only the first few months, and most babies get none against whooping cough, polio, Hib or hepatitis B (CDC). Whooping cough is most dangerous at the very start of life — about 7 in 10 whooping-cough deaths are in babies younger than 2 months, who are too young for their own DTaP shots — which is why the CDC recommends the Tdap vaccine in every pregnancy, at 27–36 weeks.

Free tool: Well-Child Checkup Calculator · UK Baby Vaccine Schedule by Birth Date

First-Year Vaccine Schedule (United States)

The list below follows the child schedule currently published by the CDC. The American Academy of Pediatrics' 2026 schedule recommends the same vaccines at these ages, and also recommends a COVID-19 vaccine for babies 6–23 months (the CDC leaves that to a shared decision with your doctor). US recommendations were revised several times in 2025–2026, so confirm the plan with your pediatrician.

Schedules Differ by Country

Every country sets its own schedule, so the same vaccine can come at a different age, or not be routine at all. Hepatitis A is a good example: it is routine at 12–23 months in the US, at 18 and 24 months in Türkiye and Saudi Arabia, and not part of the routine infant schedule in the UK or Germany. In the UK, babies start at 8 weeks (8, 12 and 16 weeks, then 1 year and 18 months), and the hepatitis B birth dose is only for babies whose mother has hepatitis B.

Official dates by birth date, from each country's own schedule: UK (NHS) · Germany (STIKO) · France · Spain · Netherlands · Türkiye · Russia · Japan · Saudi Arabia and Egypt

Parental Tips

Frequently Asked Questions

Why do babies need so many vaccines?

Newborns face the highest risk from several diseases exactly when their immune systems are least prepared. Most vaccines need more than one dose: later doses make the protection stronger and longer-lasting. The schedule times each dose to the age when a disease is most dangerous — hepatitis B starts at birth because the virus can pass from mother to baby during delivery. By their second birthday, a child who follows the US schedule is protected against more than a dozen serious diseases.

Are vaccines safe for newborns?

Yes. Vaccines licensed in the US, UK and EU go through several phases of clinical trials before they are used in babies, and safety monitoring continues after licensing. The most common reactions are mild: a sore leg, a low fever or fussiness for a day or two. Severe allergic reactions (anaphylaxis) are very rare — roughly 1 to 2 per million doses — and clinics keep epinephrine on hand for that reason. The diseases vaccines prevent, such as whooping cough, Hib meningitis and rotavirus dehydration, are far more dangerous for babies than the vaccines.

Can I spread side effects to unvaccinated siblings?

No. Soreness, fever and fussiness happen inside your baby's body and can't spread. The only nuance is the oral rotavirus vaccine, a weakened live virus: in the CDC's data, some babies shed vaccine virus in their stool for up to about 15 days after a dose. The CDC does not treat a family member with a weakened immune system as a reason to skip the vaccine; washing hands well after nappy changes is a sensible precaution.

What if my baby misses a vaccine appointment?

Call your pediatrician's office as soon as you realise. You never have to restart a series: your baby continues from the last dose given, keeping the minimum gaps between doses (CDC catch-up guidance). A gap leaves your baby less protected for a while, especially against whooping cough and Hib, so sooner is better.

Can vaccines cause autism?

No. The 1998 Lancet paper that first suggested an MMR–autism link was retracted in 2010 after an investigation found the data had been manipulated, and the lead author lost his medical licence. Since then, a 2014 review of studies covering more than 1.2 million children and a 2019 Danish study of more than 650,000 children found no link. In December 2025 the WHO's Global Advisory Committee on Vaccine Safety reviewed 31 studies published between 2010 and 2025 and again found no evidence that vaccines cause autism; the American Academy of Pediatrics says the same.

What are normal vaccine side effects?

The most common reactions are a red or swollen patch where the shot went in, a low fever, fussiness and a smaller appetite for a day or two — signs the immune system is responding. They usually start within 24 hours and settle within 48 hours. Call your pediatrician now if a baby under 12 weeks has any fever (give no fever medicine before your baby is seen), if the fever is above 104°F (40°C), or if crying doesn't stop for more than 3 hours. Call 911 for trouble breathing or if your baby is very weak or can't be woken (AAP).

Why can't I choose which vaccines to delay?

The schedule is built around the ages when each disease is most dangerous and when vaccines work best. Delaying the 2-month DTaP, for example, leaves your baby unprotected against whooping cough at the age when it is most often deadly. The AAP's 2016 clinical report on vaccine hesitancy states that no alternative schedule has been evaluated and found to be safer or more effective than the recommended one; spreading shots out only makes the unprotected period longer.

What happens if I don't vaccinate?

Unvaccinated babies have no trained defence against measles, whooping cough, Hib meningitis or polio. About 1 in 1,000 children who get measles develop encephalitis, a swelling of the brain (CDC), and whooping cough is most dangerous in the first months of life. These are not historical risks: measles and whooping cough outbreaks still happen where vaccination rates fall. Unvaccinated children also weaken the protection of babies who are too young or medically unable to be vaccinated.

Looking for an app that helps with this? See our comparison: Best Vaccination & Checkup Tracker Apps (2026): How to Choose the Right One.

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